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TRAIL limits excessive host immune responses in bacterial meningitis

TRAIL limits excessive host immune responses in bacterial meningitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1888568

TRAIL limits excessive host immune responses in bacterial meningitis

About this item

Full title

TRAIL limits excessive host immune responses in bacterial meningitis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2007-07, Vol.117 (7), p.2004-2013

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Apart from potential roles in anti-tumor surveillance, the TNF-related apoptosis-inducing ligand (TRAIL) has important regulatory functions in the host immune response. We studied antiinflammatory effects of endogenous and recombinant TRAIL (rTRAIL) in experimental meningitis. Following intrathecal application of pneumococcal cell wall, a TLR2 liga...

Alternative Titles

Full title

TRAIL limits excessive host immune responses in bacterial meningitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1888568

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1888568

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI30356

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