Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement
Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement
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Author / Creator
Dalley, Jeffrey W. , Fryer, Tim D. , Brichard, Laurent , Robinson, Emma S. J. , Theobald, David E. H. , Lääne, Kristjan , Peña, Yolanda , Murphy, Emily R. , Shah, Yasmene , Probst, Katrin , Abakumova, Irina , Aigbirhio, Franklin I. , Richards, Hugh K. , Hong, Young , Baron, Jean-Claude , Everitt, Barry J. and Robbins, Trevor W.
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Stimulant addiction is often linked to excessive risk taking, sensation seeking, and impulsivity, but in ways that are poorly understood. We report here that a form of impulsivity in rats predicts high rates of intravenous cocaine self-administration and is associated with changes in dopamine (DA) function before drug exposure. Using positron emiss...
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Full title
Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1892797
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1892797
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1137073
