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MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1913485

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

About this item

Full title

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2313-2324

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cell surface mucin glycoproteins are highly expressed by all mucosal tissues, yet their physiological role is currently unknown. We hypothesized that cell surface mucins protect mucosal cells from infection. A rapid progressive increase in gastrointestinal expression of mucin 1 (Muc1) cell surface mucin followed infection of mice with the bacterial...

Alternative Titles

Full title

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1913485

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1913485

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/jci26705

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