Whole-Genome Association Study of Major Determinants for Host Control of HIV-1
Whole-Genome Association Study of Major Determinants for Host Control of HIV-1
About this item
Full title
Author / Creator
Fellay, Jacques , Shianna, Kevin V , Ge, Dongliang , Colombo, Sara , Ledergerber, Bruno , Weale, Mike , Zhang, Kunlin , Gumbs, Curtis , Castagna, Antonella , Cossarizza, Andrea , Cozzi-Lepri, Alessandro , De Luca, Andrea , Easterbrook, Philippa , Francioli, Patrick , Mallal, Simon , Martinez-Picado, Javier , Miro, José M , Obel, Niels , Smith, Jason P , Wyniger, Josiane , Descombes, Patrick , Antonarakis, Stylianos E , Letvin, Norman L , McMichael, Andrew J , Haynes, Barton F , Telenti, Amalio and Goldstein, David B
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Understanding why some people establish and maintain effective control of HIV-1 and others do not is a priority in the effort to develop new treatments for HIV/AIDS. Using a whole-genome association strategy, we identified polymorphisms that explain nearly 15% of the variation among individuals in viral load during the asymptomatic set-point period...
Alternative Titles
Full title
Whole-Genome Association Study of Major Determinants for Host Control of HIV-1
Authors, Artists and Contributors
Author / Creator
Shianna, Kevin V
Ge, Dongliang
Colombo, Sara
Ledergerber, Bruno
Weale, Mike
Zhang, Kunlin
Gumbs, Curtis
Castagna, Antonella
Cossarizza, Andrea
Cozzi-Lepri, Alessandro
De Luca, Andrea
Easterbrook, Philippa
Francioli, Patrick
Mallal, Simon
Martinez-Picado, Javier
Miro, José M
Obel, Niels
Smith, Jason P
Wyniger, Josiane
Descombes, Patrick
Antonarakis, Stylianos E
Letvin, Norman L
McMichael, Andrew J
Haynes, Barton F
Telenti, Amalio
Goldstein, David B
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1991296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1991296
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1143767
