Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1
Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Local protein synthesis regulates the turning of growth cones to guidance cues, yet little is known about which proteins are synthesized or how they contribute to directional steering. Here we show that β-actin mRNA resides in
Xenopus laevis
retinal growth cones where it binds to the RNA-binding protein Vg1RBP. Netrin-1 induces the movement o...
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Full title
Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1997306
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1997306
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1775
