Establishment of Methylation-Sensitive-Representational Difference Analysis and Isolation of Hypo- a...
Establishment of Methylation-Sensitive-Representational Difference Analysis and Isolation of Hypo- and Hypermethylated Genomic Fragments in Mouse Liver Tumors
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
Methylation of CpG sites in the genome, which is generally conserved during cell replication, is considered to play important roles in cell differentiation and carcinogenesis. However, investigations on changes in methylation status have been limited to known genes. To make a genome-wide search for differentially methylated genes, we developed a me...
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Full title
Establishment of Methylation-Sensitive-Representational Difference Analysis and Isolation of Hypo- and Hypermethylated Genomic Fragments in Mouse Liver Tumors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_20079
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_20079
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.6.2284
