Roflumilast inhibits leukocyte‐endothelial cell interactions, expression of adhesion molecules and m...
Roflumilast inhibits leukocyte‐endothelial cell interactions, expression of adhesion molecules and microvascular permeability
About this item
Full title
Author / Creator
Sanz, M‐J , Cortijo, J , Taha, M A , Cerdá‐Nicolás, M , Schatton, E , Burgbacher, B , Klar, J , Tenor, H , Schudt, C , Issekutz, A C , Hatzelmann, A and Morcillo, E J
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
Subjects
More information
Scope and Contents
Contents
Background and purpose:
The present study addressed the effects of the investigational PDE4 inhibitor roflumilast on leukocyte‐endothelial cell interactions and endothelial permeability in vivo and in vitro.
Experimental approach:
In vivo, intravital video‐microscopy was used to determine effects of roflumilast p.o. on leukocyte‐endothelia...
Alternative Titles
Full title
Roflumilast inhibits leukocyte‐endothelial cell interactions, expression of adhesion molecules and microvascular permeability
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2050829
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2050829
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0707428
