Embryonic Exposure to Domoic Acid Increases the Susceptibility of Zebrafish Larvae to the Chemical C...
Embryonic Exposure to Domoic Acid Increases the Susceptibility of Zebrafish Larvae to the Chemical Convulsant Pentylenetetrazole
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Author / Creator
Publisher
United States: National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare
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Language
English
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Publication information
Publisher
United States: National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare
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Contents
Background: Domoic acid (DA) is a neurotoxin produced by diatoms of the genus Pseudonitzschia that targets the limbic system to induce tonic-clonic seizures and memory impairment. In utero DA exposure of mice leads to a reduction in seizure threshold to subsequent DA exposures in mid-postnatal life, and similar studies have shown neurotoxic effects...
Alternative Titles
Full title
Embryonic Exposure to Domoic Acid Increases the Susceptibility of Zebrafish Larvae to the Chemical Convulsant Pentylenetetrazole
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2072828
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2072828
Other Identifiers
ISSN
0091-6765
E-ISSN
1552-9924
DOI
10.1289/ehp.10344
