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Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease

Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2117861

Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease

About this item

Full title

Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease

Publisher

London: BMJ Publishing Group Ltd

Journal title

Journal of neurology, neurosurgery and psychiatry, 2007-09, Vol.78 (9), p.944-948

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

Objective: The safety and tolerability of adjunctive tolcapone initiated simultaneously with levodopa was evaluated with a focus on increases in liver transaminase and hepatotoxicity. Methods: 677 levodopa-naïve patients with early stage Parkinson’s disease (PD) were randomised to receive placebo or tolcapone 100 mg three times daily, added to stan...

Alternative Titles

Full title

Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2117861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2117861

Other Identifiers

ISSN

0022-3050

E-ISSN

1468-330X

DOI

10.1136/jnnp.2006.097154

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