Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease
Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease
About this item
Full title
Author / Creator
Lees, A J , Ratziu, V , Tolosa, E and Oertel, W H
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
Objective: The safety and tolerability of adjunctive tolcapone initiated simultaneously with levodopa was evaluated with a focus on increases in liver transaminase and hepatotoxicity. Methods: 677 levodopa-naïve patients with early stage Parkinson’s disease (PD) were randomised to receive placebo or tolcapone 100 mg three times daily, added to stan...
Alternative Titles
Full title
Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson’s disease
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2117861
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2117861
Other Identifiers
ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp.2006.097154