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ATM Binds to β -adaptin in Cytoplasmic Vesicles

ATM Binds to β -adaptin in Cytoplasmic Vesicles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_21476

ATM Binds to β -adaptin in Cytoplasmic Vesicles

About this item

Full title

ATM Binds to β -adaptin in Cytoplasmic Vesicles

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (17), p.10146-10151

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Inherited mutations in the ATM gene lead to a complex clinical phenotype characterized by neuronal degeneration, oculocutaneous telangiectasias, immune dysfunction, and cancer predisposition. Using the yeast two-hybrid system, we demonstrate that ataxia telangiectasia mutated (ATM) binds to β -adaptin, one of the components of the AP-2 adaptor comp...

Alternative Titles

Full title

ATM Binds to β -adaptin in Cytoplasmic Vesicles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_21476

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_21476

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.95.17.10146

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