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Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epit...

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2189995

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

About this item

Full title

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2007-12, Vol.152 (8), p.1172-1184

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Background and purpose:
Epithelial injury contributes to lung pathogenesis. Our work and that of others have identified the phosphoinositide‐3 kinase (PI3K)/Akt pathway as a vital component of survival in lung epithelia. Therefore, we hypothesized that pharmacological inhibition of PTEN, a major suppressor of this pathway, would enhance wound cl...

Alternative Titles

Full title

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2189995

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2189995

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0707501

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