Constitutive Cell Surface Association between CD4 and CCR5
Constitutive Cell Surface Association between CD4 and CCR5
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
HIV-1 entry into cells involves formation of a complex between gp120 of the viral envelope glycoprotein (Env), a receptor (CD4), and a coreceptor. For most strains of HIV, this coreceptor is CCR5. Here, we provide evidence that CD4 is specifically associated with CCR5 in the absence of gp120 or any other receptor-specific ligand. The amount of CD4...
Alternative Titles
Full title
Constitutive Cell Surface Association between CD4 and CCR5
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_22114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_22114
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.96.13.7496