Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease...
Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats
About this item
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Author / Creator
Simonides, Warner S. , Mulcahey, Michelle A. , Redout, Everaldo M. , Muller, Alice , Zuidwijk, Marian J. , Visser, Theo J. , Wassen, Frank W.J.S. , Crescenzi, Alessandra , da-Silva, Wagner S. , Harney, John , Engel, Felix B. , Obregon, Maria-Jesús , Larsen, P. Reed , Bianco, Antonio C. and Huang, Stephen A.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
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Scope and Contents
Contents
Thyroid hormone is a critical determinant of cellular metabolism and differentiation. Precise tissue-specific regulation of the active ligand 3,5,3'-triiodothyronine (T3) is achieved by the sequential removal of iodine groups from the thyroid hormone molecule, with type 3 deiodinase (D3) comprising the major inactivating pathway that terminates the...
Alternative Titles
Full title
Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2230657
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2230657
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI32824
