Supramolecular Organization of Immature and Mature Murine Leukemia Virus Revealed by Electron Cryo-M...
Supramolecular Organization of Immature and Mature Murine Leukemia Virus Revealed by Electron Cryo-Microscopy: Implications for Retroviral Assembly Mechanisms
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United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
We have used electron cryo-microscopy and image analysis to examine the native structure of immature, protease-deficient (PR-) and mature, wild-type (WT) Moloney murine leukemia virus (MuLV). Maturational cleavage of the Gag polyprotein by the viral protease is associated with striking morphological changes. The PR-MuLV particles exhibit a rounded...
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Full title
Supramolecular Organization of Immature and Mature Murine Leukemia Virus Revealed by Electron Cryo-Microscopy: Implications for Retroviral Assembly Mechanisms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_22596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_22596
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.95.13.7299
