IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
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Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Tumors elicit antitumor immune responses, but over time they evolve and can escape immune control through various mechanisms, including the loss of the antigen to which the response is directed. The escape of antigen-loss variants (ALVs) is a major obstacle to T cell-based immunotherapy for cancer. However, cancers can be cured if both the number o...
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Full title
IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2262029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2262029
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI33522
