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The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak...

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2275436

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?

About this item

Full title

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

British journal of pharmacology, 2008-03, Vol.153 (6), p.1105-1119

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

There is considerable evidence that the potent vasoconstrictor endothelin‐1 (ET‐1) contributes to the pathogenesis of a variety of cardiovascular diseases. As such, pharmacological manipulation of the ET system might represent a promising therapeutic goal. Many clinical trials have assessed the potential of ET receptor antagonists in cardiovascular...

Alternative Titles

Full title

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2275436

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2275436

Other Identifiers

ISSN

0007-1188

E-ISSN

1476-5381

DOI

10.1038/sj.bjp.0707516

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