Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia
Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Polyglutamine disorders are inherited neurodegenerative diseases caused by the accumulation of expanded polyglutamine protein (polyQ). Previously, we identified a new guanosine triphosphatase, CRAG, which facilitates the degradation of polyQ aggregates through the ubiquitin–proteasome pathway in cultured cells. Because expression of CRAG decreases...
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Full title
Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2288764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2288764
Other Identifiers
ISSN
1469-221X
E-ISSN
1469-3178,1469-221X
DOI
10.1038/embor.2008.31
