Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effect...
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo
About this item
Full title
Author / Creator
Theys, J , Pennington, O , Dubois, L , Anlezark, G , Vaughan, T , Mengesha, A , Landuyt, W , Anné, J , Burke, P J , Dûrre, P , Wouters, B G , Minton, N P and Lambin, P
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The unique properties of the tumour microenvironment can be exploited by using recombinant anaerobic clostridial spores as highly selective gene delivery vectors. Although several recombinant
Clostridium
species have been generated during the past decade, their efficacy has been limited. Our goal was to substantially improve the prospects of...
Alternative Titles
Full title
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2360559
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2360559
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6603367
