Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian c...
Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian cancer
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Author / Creator
Levitt, N C , Propper, D J , Madhusudan, S , Braybrooke, J P , Echeta, C , te Poele, R , Davies, S L , Flanagan, E , Hickson, I D , Joel, S and Ganesan, T S
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A pharmacokinetically guided phase I study of topotecan and etoposide phosphate was conducted in recurrent ovarian cancer. The scheduling of the topoisomerase I and II inhibitors was determined using
in vitro
activity data. All patients had recurrent disease following prior platinum-containing chemotherapy. Patients had a World Health Organis...
Alternative Titles
Full title
Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361471
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6602657