Expansion of a CUG Trinucleotide Repeat in the 3′Untranslated Region of Myotonic Dystrophy Protein K...
Expansion of a CUG Trinucleotide Repeat in the 3′Untranslated Region of Myotonic Dystrophy Protein Kinase Transcripts Results in Nuclear Retention of Transcripts
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
Expansion of a CTG trinucleotide repeat in the 3′untranslated region (UTR) of DMPK, the gene encoding myotonic dystrophy protein kinase, induces the dominantly inherited neuromuscular disorder myotonic dystrophy (DM). Transcripts containing the expanded trinucleotide are abundant in differentiated cultured myoblasts, and they are spliced and polyad...
Alternative Titles
Full title
Expansion of a CUG Trinucleotide Repeat in the 3′Untranslated Region of Myotonic Dystrophy Protein Kinase Transcripts Results in Nuclear Retention of Transcripts
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_23831
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_23831
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.14.7388
