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Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent hum...

Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent hum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2386253

Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity

About this item

Full title

Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity

Publisher

New York: Nature Publishing Group US

Journal title

Nature Immunology, 2006-10, Vol.7 (10), p.1082-1091

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

TFE3 and TFEB are broadly expressed transcription factors related to the transcription factor Mitf. Although they have been linked to cytokine signaling pathways in nonlymphoid cells, their function in T cells is unknown. TFE3-deficient mice are phenotypically normal, whereas TFEB deficiency causes early embryonic death. We now show that combined i...

Alternative Titles

Full title

Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2386253

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2386253

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916,1365-2567

DOI

10.1038/ni1378

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