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Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neuron...

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neuron...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2516882

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

About this item

Full title

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2008-08, Vol.27 (15), p.2124-2134

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

The transport of vesicles in neurons is a highly regulated process, with vesicles moving either anterogradely or retrogradely depending on the nature of the molecular motors, kinesins and dynein, respectively, which propel vesicles along microtubules (MTs). However, the mechanisms that determine the directionality of transport remain unclear. Hunti...

Alternative Titles

Full title

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2516882

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2516882

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2008.133

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