TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vi...
TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Genital coinfections increase an individual's risk of becoming infected with HIV-1 by sexual contact. Several mechanisms have been proposed to explain this, such as the presence of ulceration and bleeding caused by the coinfecting pathogen. Here we demonstrate that Langerhans cells (LCs) are involved in the increased susceptibility to HIV-1 in the...
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Full title
TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2528910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2528910
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI34721