Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells
Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
The prevention of autoimmunity requires the elimination of self-reactive T cells during their development and maturation. The expression of diverse self-antigens by stromal cells in the thymus is essential to this process and depends, in part, on the activity of the autoimmune regulator (Aire) gene. Here we report the identification of extrathymic...
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Full title
Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2532844
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2532844
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ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1159407
