Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
MicroRNAs (miRNAs) are ~22-nucleotide RNAs that can pair to sites within messenger RNAs to specify posttranscriptional repression of these messages. Aberrant miRNA expression can contribute to tumorigenesis, but which of the many miRNA-target relationships are relevant to this process has been unclear. Here, we report that chromosomal translocation...
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Full title
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2556962
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2556962
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1137999
