Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
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Author / Creator
Rogers, Christopher S , Stoltz, David A , Meyerholz, David K , Ostedgaard, Lynda S , Rokhlina, Tatiana , Taft, Peter J , Rogan, Mark P , Pezzulo, Alejandro A , Karp, Philip H , Itani, Omar A , Kabel, Amanda C , Wohlford-Lenane, Christine L , Davis, Greg J , Hanfland, Robert A , Smith, Tony L , Samuel, Melissa , Wax, David , Murphy, Clifton N , Rieke, August , Whitworth, Kristin , Uc, Aliye , Starner, Timothy D , Brogden, Kim A , Shilyansky, Joel , McCray, Paul B. Jr , Zabner, Joseph , Prather, Randall S and Welsh, Michael J
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Almost two decades after CFTR was identified as the gene responsible for cystic fibrosis (CF), we still lack answers to many questions about the pathogenesis of the disease, and it remains incurable. Mice with a disrupted CFTR gene have greatly facilitated CF studies, but the mutant mice do not develop the characteristic manifestations of human CF,...
Alternative Titles
Full title
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
Authors, Artists and Contributors
Author / Creator
Stoltz, David A
Meyerholz, David K
Ostedgaard, Lynda S
Rokhlina, Tatiana
Taft, Peter J
Rogan, Mark P
Pezzulo, Alejandro A
Karp, Philip H
Itani, Omar A
Kabel, Amanda C
Wohlford-Lenane, Christine L
Davis, Greg J
Hanfland, Robert A
Smith, Tony L
Samuel, Melissa
Wax, David
Murphy, Clifton N
Rieke, August
Whitworth, Kristin
Uc, Aliye
Starner, Timothy D
Brogden, Kim A
Shilyansky, Joel
McCray, Paul B. Jr
Zabner, Joseph
Prather, Randall S
Welsh, Michael J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2570747
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2570747
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1163600
