CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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High-conductance, Ca
2+
-activated and voltage-gated (BK) channels set neuronal firing. They are almost universally activated by alcohol, leading to reduced neuronal excitability and neuropeptide release and to motor intoxication. However, several BK channels are inhibited by alcohol, and most other voltage-gated K
+
channels are refrac...
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CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574430
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574430
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1602