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CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels

CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574430

CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels

About this item

Full title

CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels

Publisher

London: Nature Publishing Group UK

Journal title

Nature neuroscience, 2006-01, Vol.9 (1), p.41-49

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

High-conductance, Ca
2+
-activated and voltage-gated (BK) channels set neuronal firing. They are almost universally activated by alcohol, leading to reduced neuronal excitability and neuropeptide release and to motor intoxication. However, several BK channels are inhibited by alcohol, and most other voltage-gated K
+
channels are refrac...

Alternative Titles

Full title

CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574430

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574430

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn1602

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