PRDM16 controls a brown fat/skeletal muscle switch
PRDM16 controls a brown fat/skeletal muscle switch
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Brown fat can increase energy expenditure and protect against obesity through a specialized program of uncoupled respiration. Here we show by
in vivo
fate mapping that brown, but not white, fat cells arise from precursors that express
Myf5
, a gene previously thought to be expressed only in the myogenic lineage. We also demonstrate that...
Alternative Titles
Full title
PRDM16 controls a brown fat/skeletal muscle switch
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2583329
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2583329
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature07182