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Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary a...

Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2586587

Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats

About this item

Full title

Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats

Publisher

United States: The Biophysical Society

Journal title

Biophysical journal, 2008-12, Vol.95 (11), p.5165-5177

Language

English

Formats

Publication information

Publisher

United States: The Biophysical Society

More information

Scope and Contents

Contents

The large-conductance Ca(2+)-activated K(+) (BK) channels play an important role in the regulation of cellular excitability in response to changes in intracellular metabolic state and Ca(2+) homeostasis. In vascular smooth muscle, BK channels are key determinants of vasoreactivity and vital-organ perfusion. Vascular BK channel functions are impaire...

Alternative Titles

Full title

Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2586587

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2586587

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

DOI

10.1529/biophysj.108.138339

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