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Activating mutations in ALK provide a therapeutic target in neuroblastoma

Activating mutations in ALK provide a therapeutic target in neuroblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2587486

Activating mutations in ALK provide a therapeutic target in neuroblastoma

About this item

Full title

Activating mutations in ALK provide a therapeutic target in neuroblastoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2008-10, Vol.455 (7215), p.975-978

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neuroblastoma: a genetic link to ALK
Neuroblastoma is the most common childhood cancer. There is a strong familial association and it was predicted over 30 years ago that there was a genetic element to the disease. Four groups now report the identification of mutations in the tyrosine kinase receptor ALK (anaplastic lymphoma kinase) in neuroblas...

Alternative Titles

Full title

Activating mutations in ALK provide a therapeutic target in neuroblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2587486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2587486

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature07397

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