A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Maintaining energy balance in fasting
A fasting-inducible switch, consisting of the histone acetyl transferase p300 and the nutrient-sensing NAD
+
-dependent deacetylase SIRT1, is shown to maintain energy balance during fasting by promoting the sequential induction of the transcription factors TORC2 and FOXO1. This illustrates how the exch...
Alternative Titles
Full title
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2597669
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2597669
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature07349
