Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in t...
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary
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Author / Creator
Blum, Kenneth , Chen, Amanda Lih Chuan , Chen, Thomas J H , Braverman, Eric R , Reinking, Jeffrey , Blum, Seth H , Cassel, Kimberly , Downs, Bernard W , Waite, Roger L , Williams, Lonna , Prihoda, Thomas J , Kerner, Mallory M , Palomo, Tomas , Comings, David E , Tung, Howard , Rhoades, Patrick and Oscar-Berman, Marlene
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Based on neurochemical and genetic evidence, we suggest that both prevention and treatment of multiple addictions, such as dependence to alcohol, nicotine and glucose, should involve a biphasic approach. Thus, acute treatment should consist of preferential blocking of postsynaptic Nucleus Accumbens (NAc) dopamine receptors (D1-D5), whereas long ter...
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Full title
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2615745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2615745
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ISSN
1742-4682
E-ISSN
1742-4682
DOI
10.1186/1742-4682-5-24
