α-Methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis th...
α-Methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis therapy
About this item
Full title
Author / Creator
Schluep, Thomas , Hwang , Rodgers and Oliver
Publisher
New Zealand: Taylor & Francis Ltd
Journal title
Language
English
Formats
Publication information
Publisher
New Zealand: Taylor & Francis Ltd
Subjects
More information
Scope and Contents
Contents
A glycinate derivative of alpha-methylprednisolone (MP) was prepared and conjugated to a linear cyclodextrin polymer (CDP) with a loading of 12.4% w/w. The polymer conjugate (CDP-MP) self-assembled into nanoparticles with a size of 27 nm. Release kinetics of MP from the polymer conjugate showed a half-life (t1/2) of 50 h in phosphate buffer solutio...
Alternative Titles
Full title
α-Methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis therapy
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2626937
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2626937
Other Identifiers
ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S3217
