COMT Genotype Influences the Effect of Alcohol on Blood Pressure: Results From the COMBINE Study
COMT Genotype Influences the Effect of Alcohol on Blood Pressure: Results From the COMBINE Study
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Basingstoke: Oxford University Press
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Language
English
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Basingstoke: Oxford University Press
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Background Heavy drinking can cause chronic hypertension, possibly due to effects on the autonomic nervous system. Catechol- O-methyltransferase (COMT) inactivates catecholamines, and a G to A substitution in codon 108 in the soluble COMT mRNA (or codon 158 in the membrane-bound form) substitutes methionine for valine and alters enzyme activity. Me...
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Full title
COMT Genotype Influences the Effect of Alcohol on Blood Pressure: Results From the COMBINE Study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2630169
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2630169
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ISSN
0895-7061
E-ISSN
1941-7225
DOI
10.1038/ajh.2008.321
