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CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1...

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2630879

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1–infected individuals

About this item

Full title

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1–infected individuals

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2008-04, Vol.14 (4), p.413-420

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The basis for the extensive variability seen in the reconstitution of CD4
+
T cell counts in HIV-infected individuals receiving highly active antiretroviral therapy (HAART) is not fully known. Here, we show that variations in
CCL3L1
gene dose and
CCR5
genotype, but not major histocompatibility complex HLA alleles, influence immune...

Alternative Titles

Full title

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1–infected individuals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2630879

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2630879

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1741

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