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The aurora kinase A regulates GSK-3β in gastric cancer cells

The aurora kinase A regulates GSK-3β in gastric cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2642527

The aurora kinase A regulates GSK-3β in gastric cancer cells

About this item

Full title

The aurora kinase A regulates GSK-3β in gastric cancer cells

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2009-02, Vol.28 (6), p.866-875

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aurora kinase A (AURKA) is located at 20q13, a region that is frequently amplified in gastric cancer. In this study, we have investigated the role of AURKA in regulating glycogen synthase kinase (GSK)-3β and β-catenin/TCF complex in gastric cancer cells. Our results demonstrate a significant increase in the phosphorylation of GSK-3β at Ser 9 follow...

Alternative Titles

Full title

The aurora kinase A regulates GSK-3β in gastric cancer cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2642527

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2642527

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2008.434

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