Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation...
Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy
About this item
Full title
Author / Creator
Harada, H , Itasaka, S , Zhu, Y , Zeng, L , Xie, X , Morinibu, A , Shinomiya, K and Hiraoka, M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hypoxia-inducible factor-1 (HIF-1) has been reported to promote tumour radioresistance; therefore, it is recognised as an excellent target during radiation therapy. However, the inhibition of HIF-1 in unsuitable timing can suppress rather than enhance the effect of radiation therapy because its anti-angiogenic effect increases the radioresistant hy...
Alternative Titles
Full title
Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2653764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2653764
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6604939
