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Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzhe...

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzhe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2656563

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

About this item

Full title

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

Author / Creator

Publisher

Oak Park, IL: Bentham Science Publishers Ltd

Journal title

Current medicinal chemistry, 2008-10, Vol.15 (23), p.2321-2328

Language

English

Formats

Publication information

Publisher

Oak Park, IL: Bentham Science Publishers Ltd

More information

Scope and Contents

Contents

Alzheimer disease (AD) is the most common cause of dementia in adults. The current therapy for AD has only moderate efficacy in controlling symptoms, and it does not cure the disease. Recent studies have suggested that abnormal hyperphosphorylation of tau in the brain plays a vital role in the molecular pathogenesis of AD and in neurodegeneration....

Alternative Titles

Full title

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2656563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2656563

Other Identifiers

ISSN

0929-8673

E-ISSN

1875-533X

DOI

10.2174/092986708785909111

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