Noncytotoxic Lytic Granule-Mediated CD8⁺ T Cell Inhibition of HSV-1 Reactivation from Neuronal Laten...
Noncytotoxic Lytic Granule-Mediated CD8⁺ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency
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Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Reactivation of herpes simplex virus type 1 (HSV-1) from neuronal latency is a common and potentially devastating cause of disease worldwide. CD8⁺ T cells can completely inhibit HSV reactivation in mice, with interferon-γ affording a portion of this protection. We found that CD8⁺ T cell lytic granules are also required for the maintenance of neuron...
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Full title
Noncytotoxic Lytic Granule-Mediated CD8⁺ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680315
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680315
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1164164
