Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
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Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
At least eight types of ubiquitin chain exist, and individual linkages affect distinct cellular processes. The only distinguishing feature of differently linked ubiquitin chains is their structure, as polymers of the same unit are chemically identical. Here, we have crystallized Lys 63‐linked and linear ubiquitin dimers, revealing that both adopt e...
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Full title
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680876
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680876
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ISSN
1469-221X
E-ISSN
1469-3178
DOI
10.1038/embor.2009.55