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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680876

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

About this item

Full title

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

EMBO reports, 2009-05, Vol.10 (5), p.466-473

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

At least eight types of ubiquitin chain exist, and individual linkages affect distinct cellular processes. The only distinguishing feature of differently linked ubiquitin chains is their structure, as polymers of the same unit are chemically identical. Here, we have crystallized Lys 63‐linked and linear ubiquitin dimers, revealing that both adopt e...

Alternative Titles

Full title

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680876

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2680876

Other Identifiers

ISSN

1469-221X

E-ISSN

1469-3178

DOI

10.1038/embor.2009.55

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