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CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695655

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

About this item

Full title

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5909), p.1843-1845

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the latter is particularly important for the spread of antibiotic resistance. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci confer sequence-directed immunity against phages. A clinical isolate of S...

Alternative Titles

Full title

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695655

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1165771

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