CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
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United States: American Association for the Advancement of Science
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Language
English
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United States: American Association for the Advancement of Science
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Contents
Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the latter is particularly important for the spread of antibiotic resistance. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci confer sequence-directed immunity against phages. A clinical isolate of S...
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Full title
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695655
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695655
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1165771