Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Changes in the composition of glycans added to glycoproteins and glycolipids are characteristic of the change to malignancy. Sialyl-Tn (STn) is expressed by 25–30% of breast carcinomas but its expression on normal tissue is highly restricted. Sialyl-Tn is an
O
-linked disaccharide that can be carried on various glycoproteins. One such glycopr...
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Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695689
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2695689
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6605083