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Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2717141

Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

About this item

Full title

Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

Publisher

United States: National Institute of Environmental Health Sciences

Journal title

Environmental health perspectives, 2009-07, Vol.117 (7), p.1131-1138

Language

English

Formats

Publication information

Publisher

United States: National Institute of Environmental Health Sciences

More information

Scope and Contents

Contents

Background: Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the "3 Rs" (reduction, replacement, and refinement) of animal testing and the European regulation of chemicals [Registr...

Alternative Titles

Full title

Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2717141

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2717141

Other Identifiers

ISSN

0091-6765

E-ISSN

1552-9924

DOI

10.1289/ehp.0800207

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