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Tumor Necrosis Factor–α Overexpression in Lung Disease: A Single Cause behind a Complex Phenotype

Tumor Necrosis Factor–α Overexpression in Lung Disease: A Single Cause behind a Complex Phenotype

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2718479

Tumor Necrosis Factor–α Overexpression in Lung Disease: A Single Cause behind a Complex Phenotype

About this item

Full title

Tumor Necrosis Factor–α Overexpression in Lung Disease: A Single Cause behind a Complex Phenotype

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2005-06, Vol.171 (12), p.1363-1370

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Tumor necrosis factor alpha (TNF-alpha) has been implicated as a key cytokine in many inflammatory lung diseases. These effects are currently unclear, because a transgenic mouse overexpressing TNF-alpha in the lung has been shown in separate studies to produce elements of both emphysema and pulmonary fibrosis.
We sought to elucidate the phenotyp...

Alternative Titles

Full title

Tumor Necrosis Factor–α Overexpression in Lung Disease: A Single Cause behind a Complex Phenotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2718479

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2718479

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.200410-1349OC

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