Prognostic and predictive value of common mutations for treatment response and survival in patients...
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
About this item
Full title
Author / Creator
Souglakos, J , Philips, J , Wang, R , Marwah, S , Silver, M , Tzardi, M , Silver, J , Ogino, S , Hooshmand, S , Kwak, E , Freed, E , Meyerhardt, J A , Saridaki, Z , Georgoulias, V , Finkelstein, D , Fuchs, C S , Kulke, M H and Shivdasani, R A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background:
We address the prognostic and predictive value of
KRAS
,
PIK3CA
and
BRAF
mutations for clinical outcomes in response to active agents in the treatment of metastatic colorectal cancer (mCRC).
Methods:
We determined
KRAS
,
BRAF
and
PIK3CA
mutations in tumours from 168 patients treated for mCRC...
Alternative Titles
Full title
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2720232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2720232
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6605164
