β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
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Author / Creator
Loulier, Karine , Lathia, Justin D. , Marthiens, Veronique , Relucio, Jenne , Mughal, Mohamed R. , Tang, Sung-Chun , Coksaygan, Turhan , Hall, Peter E. , Chigurupati, Srinivasulu , Patton, Bruce , Colognato, Holly , Rao, Mahendra S. , Mattson, Mark P. , Haydar, Tarik F. and ffrench-Constant, Charles
Publisher
San Francisco, USA: Public Library of Science
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Language
English
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Publisher
San Francisco, USA: Public Library of Science
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Contents
IInteractions between laminins and integrin receptors hold neural stem cells in place at the ventricular surface of embryonic brain. Transient disruption leads to abnormal stem cell divisions and permanent cortical malformation.
During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zon...
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Full title
β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2720642
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2720642
Other Identifiers
ISSN
1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1000176
