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Genome Engineering-Based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a N...

Genome Engineering-Based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a N...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2728851

Genome Engineering-Based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a Nonessential Function in Lateral Inhibition in Drosophila

About this item

Full title

Genome Engineering-Based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a Nonessential Function in Lateral Inhibition in Drosophila

Publisher

United States: Genetics Soc America

Journal title

Genetics (Austin), 2009-08, Vol.182 (4), p.1101-1108

Language

English

Formats

Publication information

Publisher

United States: Genetics Soc America

More information

Scope and Contents

Contents

Lateral inhibition mediated by Notch receptor signaling regulates the determination of sensory organ precursor cells (SOPs) in Drosophila. The selection of SOPs from proneural cluster cells appears to rely on a negative feedback loop linking activation of the Notch receptor to downregulation of its ligand Delta within each cell. The molecular basis...

Alternative Titles

Full title

Genome Engineering-Based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a Nonessential Function in Lateral Inhibition in Drosophila

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2728851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2728851

Other Identifiers

ISSN

0016-6731,1943-2631

E-ISSN

1943-2631

DOI

10.1534/genetics.109.105023

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