Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A‐type lamins are intermediate filament proteins that provide a scaffold for protein complexes regulating nuclear structure and function. Mutations in the
LMNA
gene are linked to a variety of degenerative disorders termed laminopathies, whereas changes in the expression of lamins are associated with tumourigenesis. The molecular pathways affe...
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Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735177
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735177
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ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2009.196