Linking the p53 tumour suppressor pathway to somatic cell reprogramming
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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On iPS cells and p53: somatic cell reprogramming
This paper reports that the transcription factor p53 plays a crucial role in regulating somatic reprogramming. The authors develop an experimental protocol to reprogram somatic cells using just two factors, Oct4 and Sox2, when p53 is silenced. On the other hand, overexpression of p53 or the presen...
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Full title
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735889
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735889
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08311
