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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiat...

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2740725

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

About this item

Full title

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2008-03, Vol.14 (3), p.306-314

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Postnatal bone marrow houses mesenchymal progenitor cells that are osteoblast precursors. These cells have established therapeutic potential, but they are difficult to maintain and expand
in vitro
, presumably because little is known about the mechanisms controlling their fate decisions. To investigate the potential role of Notch signaling in...

Alternative Titles

Full title

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2740725

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2740725

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1716

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